|
KMID : 0378019670100020051
|
|
New Medical Journal
1967 Volume.10 No. 2 p.51 ~ p.60
|
|
|
Gas Exchange in Uterine Cavity of Rabbit
|
|
|
|
|
Abstract
|
|
|
This study was undertaken to elucidate the behavior of gases in the uterine cavity of rabbit initially filled with gases of various compositions. The non-pregnant rabbit was laparato mized and the uterus was exposed under the pentobarbital and urethane anesthesia. Prior to the experiment the uterus was filled with 6 ml or 2 ml of the air, the test gas whose gas composition is close to that of the blood, or pure nitrogen. The composition of the gas in the uterus cavity and the volume were determined at the 2nd, 4th, and 6th hour following the filling of gas. The same kind of experiments acre performed in the estrogen treated groups of rabbits and the results were compared with those of the normal groups. The results obtained are summerized as follows.
1. The steady state of gas composition is attained at about four hours after injection of gas in the uterus. The steady state composition of gas in the normal uterus is approximately 3% in oxygen, 5% in carbon dioxide, and 92% in nitrogen, whereas in the estrogen treated group is approximately 2% in oxygen, 5% in carbon dioxide, and 93% in nitrogen. The lower value in oxygen in the latter is attributable to the increased utilization of oxygen in the endometrial tissues.
2. The diffusion capacity of oxygen in the uterine cavity are calculated as follows making use of the experimental data under some assumptions: In the normal groups; 1.38 x 10-4 ml/min mmHg, in the estrogen treated groups; 1.11 x 10-4 ml/min mmHg. These figures are slightly greater than the reported ones in the subcutaneous gas pocket and is close to those in the urinary bladder or the intestinal cavity.
3. The thickness of diffusion barrier calculated from the experimental data under some assumptions is greater in the 2 ml injected group than in the 6 ml injected group. Such difference is attributable to the extent of distension of the uterus.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|